Plain-English translation of NCT03385720 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether surgeons can safely preserve a salivary gland called the submandibular gland during neck surgery for early-stage mouth cancer. Some patients will have this gland removed as part of standard surgery, while others will have it preserved. The goal is to see if keeping the gland improves survival rates and quality of life without compromising cancer treatment.
Removing the submandibular gland during neck surgery can cause dry mouth and other side effects that affect quality of life. Researchers want to know if preserving this gland is safe and effective for patients with early-stage mouth cancer, potentially reducing these complications.
You likely qualify if…
You likely don't qualify if…
If you qualify and enroll, you will be randomly assigned to one of two groups: one group will have neck surgery with the salivary gland preserved, and the other group will have standard surgery with the gland removed. Researchers will then track your survival rates and overall health outcomes over time to compare how well both approaches work.
AI-generated summary from trial data · Jul 6, 2026 · Not medical advice
China
Guang-Yan Yu
Collaborators
National Natural Science Foundation of China, Peking University School of Stomatology
Enrollment target
~200 participants
Started
December 2017
Primary completion
December 2023
This trial's estimated completion date has passed — the record may not be fully up to date.
Last updated on clinicaltrials.gov in March 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jia-Zeng Su, Dr.
Guang-Yan Yu
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.