Plain-English translation of NCT03398369 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether using advanced heart imaging (called CMR) to guide pacemaker placement works better than standard placement. The study includes 180 people with severely weakened hearts who need a pacemaker called CRT (cardiac resynchronization therapy). By using detailed scans to see exactly where the heart is damaged and how it's beating, doctors may be able to place the pacemaker in the best possible location.
Many people with severe heart failure get a CRT pacemaker, but it doesn't help everyone equally. This trial is testing whether using detailed heart imaging during the procedure can improve outcomes by placing the device in the most effective location for each patient.
You likely qualify if…
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You will start with baseline tests including heart scans, blood work, and exercise testing. You'll then be randomly assigned to either standard pacemaker placement or placement guided by detailed heart imaging. After the procedure, you'll return for follow-up visits at 6 and 12 months to check how you're doing. The study team will also monitor you for 3 years afterward to track your health and any complications.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
University of Virginia
Enrollment target
~180 participants
Started
January 2018
Primary completion
January 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
20 Years – 90 Years
Last updated on clinicaltrials.gov in February 2020.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kenneth C Bilchick, MD
University of Virginia Health System
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.