Plain-English translation of NCT03401879 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how multiple sclerosis affects the small blood vessels and nerves in the retina—the light-sensitive tissue at the back of your eye. This study will measure how your retina's blood vessels respond when exposed to flickering light, and compare these responses between people with MS and healthy volunteers. The goal is to discover whether these eye measurements could help doctors detect MS-related changes earlier.
Scientists know that MS damages nerves throughout the brain and spinal cord, and some of these changes also appear in the retina. However, most tests only look at the structure of the retina, not how well it actually functions. This study aims to fill that gap by measuring functional changes—how the retina's blood flow and oxygen levels respond to light—which might be a new way to track MS progression.
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If you qualify, you will visit the Medical University of Vienna for eye imaging appointments where researchers will use specialized cameras to photograph your retina and measure how your eye's blood vessels respond to flickering light. They will also measure the thickness of specific nerve layers in your retina and assess blood flow and oxygen levels in your eye. The study compares these measurements between people with MS and healthy volunteers to identify differences in how the retina functions.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Austria