Plain-English translation of NCT03423758 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying the genetic causes of three types of glaucoma — a group of eye diseases that can lead to vision loss. By comparing genetic material from people who have these conditions with healthy volunteers, they hope to identify the specific genes responsible for each type. This could help doctors diagnose glaucoma earlier and develop better treatments.
Currently, there are no reliable early warning tests for glaucoma, and many people don't know they have it until significant vision loss has already occurred. By understanding the genetic basis of these diseases, researchers hope to create better diagnostic tests and find new ways to treat glaucoma beyond just lowering eye pressure — which is the only current approach and doesn't work for everyone.
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If you qualify, you would have a clinical eye examination and provide a blood sample for genetic testing. The study is recruiting 300 participants total across all four groups (three glaucoma types plus healthy controls). Researchers will compare your genetic information to look for patterns that explain why certain people develop these eye diseases.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Austria
Sponsor
Medical University of Vienna
Enrollment target
~300 participants
Started
May 2017
Primary completion
January 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
21 Years – 105 Years
Last updated on clinicaltrials.gov in May 2025.
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Central contact
Gerhard Garhöfer
Medical University of Vienna
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