Plain-English translation of NCT03445585 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research biobank — a collection of blood, saliva, stool, urine, and tissue samples from patients with cholestatic liver diseases (like primary sclerosing cholangitis and primary biliary cirrhosis) as well as healthy volunteers and people with other liver conditions. Researchers will use these samples to study how these diseases start, progress, and to develop better ways to detect them early and predict how they will affect each person.
Cholestatic liver diseases are serious conditions that affect how bile flows through the liver. By collecting and studying biological samples from many patients over time, researchers hope to find new clues about what causes these diseases, how to spot them sooner, and how to predict which patients will develop complications.
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If you enroll, you will be asked to donate blood, saliva, stool, and urine samples — either during your regular visits to Mayo Clinic, through a mail-home collection kit, or at a local lab near you. If you are already scheduled for a specific procedure called ERCP (a procedure to check the bile ducts), doctors may also collect a small sample of bile and bile duct cells during that procedure. There is no set time limit for the study; it is designed to collect samples from you over time as part of your ongoing care and to support current and future research.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Enrollment target
~9,150 participants
Started
January 2017
Primary completion
January 2050
Age range
18 Years – 85 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Erik Schlicht, CCRP, B.A.
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.