Plain-English translation of NCT03471403 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing cold snare polypectomy, a gentler technique for removing growths (adenomas) from the duodenum—the first part of your small intestine—in people with familial adenomatous polyposis (FAP). FAP causes multiple growths throughout the digestive tract, and duodenal growths are common and need to be managed carefully. The trial will help doctors understand whether this particular removal technique is safe and effective for this specific purpose.
People with FAP develop growths in the duodenum in up to 90% of cases by age 70, and managing these growths is challenging. Current removal methods have limitations and can sometimes cause complications. This trial exists to see if the new technique offers a safer, more effective option.
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If you join this trial, you would receive the cold snare polypectomy procedure during a routine duodenoscopy (an endoscopy focused on your duodenum). This procedure is performed while you're sedated, and the doctor uses a specialized tool to gently remove the growths. You would be monitored for safety, and your outcomes would be tracked as part of the study to help doctors learn whether this technique works well for FAP patients.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
Australia
Sponsor
Western Sydney Local Health District
Enrollment target
~100 participants
Started
October 2017
Primary completion
October 2027
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Michael J Bourke, MBBS
Western Sydney Local Health District
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.