Plain-English translation of NCT03475173 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing a new type of eye imaging technology called laser speckle blood flow imaging. The goal is to see if this technology can better detect areas of damage or abnormal function in the retina (the light-sensitive tissue at the back of the eye) compared to standard vision tests.
Currently, doctors rely on several different tests to diagnose and monitor eye diseases. This study is exploring whether this new imaging technology could be a better way to detect eye problems earlier and more accurately, potentially helping patients get treated sooner.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would come in for imaging visits where doctors use the new laser speckle blood flow technology to take pictures of the back of your eye. The procedure is non-invasive, meaning nothing goes into or touches your eye—it's similar to other eye imaging tests you may have had. You may also complete standard vision tests during your visit so researchers can compare the new technology to existing methods.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Sponsor
Randy Kardon
Enrollment target
~500 participants
Started
May 2019
Primary completion
January 2028
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Julie K Nellis, BSN
University of Iowa Department of Ophthalmology
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.