Plain-English translation of NCT03476525 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
When you have weight loss surgery like gastric bypass or sleeve gastrectomy, your stomach and digestive system change significantly. This study is investigating how those changes affect how your body processes , an antidepressant medication many people take. Researchers want to understand whether patients might need different doses of this medication after surgery.
Very little is currently known about how weight loss surgery affects the way antidepressant medications work in your body. Since surgery changes your stomach's acid levels, how fast food moves through your digestive system, and how your body absorbs medications, this medication may work differently after surgery. This research could help doctors give better care to people taking antidepressants who are having weight loss surgery.
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As a participant, you would have blood samples taken at specific times before and after your weight loss surgery so researchers can measure how your body is processing the antidepressant medication. The study is very small (only 12 participants total) and focuses on gathering biological information to understand medication changes after surgery. Your participation would help doctors better understand how to prescribe antidepressants safely to future patients having similar surgery.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
Norway
St. Olavs Hospital, Volvat Medisinsk Senter Stokkan
Enrollment target
~12 participants
Started
November 2016
Primary completion
October 2026
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Magnus Strømmen, MSc
St. Olavs Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.