Plain-English translation of NCT03481881 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that follows children under 21 years old who are receiving cancer medications as part of their regular treatment. Researchers want to understand how each child's body processes and uses these medications — information that isn't yet well documented. By studying this, doctors hope to learn how to prescribe the right doses for different children.
Many medications used to treat childhood cancers haven't been thoroughly studied in children to understand how their bodies handle them. This study fills that gap by collecting real-world information about how the medication works in young patients, which can help doctors treat future patients more safely and effectively.
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You would continue taking your cancer medications exactly as your doctor has prescribed — nothing changes about your treatment. Researchers would simply collect information from your medical records about how your body is responding to the medication, and may take extra blood samples during visits you're already making for your cancer care. The study is designed to fit into your regular treatment schedule.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Enrollment target
~200 participants
Started
August 2013
Primary completion
August 2033
Age range
0 Years – 20 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachel G Greenberg, MD
Duke University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.