Plain-English translation of NCT03488953 on ClinicalTrials.gov ↗ · Source last updated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a specialized surgical approach for people with colorectal cancer that has spread to the liver in a way that cannot be treated with standard surgery alone. The procedure involves a two-stage process: first, the surgeon ties off blood flow to part of the liver to make it shrink, and then a living donor provides part of their liver for transplant. The goal is to give patients a better chance at long-term survival and being cancer-free.
Many people with colorectal cancer that spreads to the liver cannot be helped by standard surgery or chemotherapy alone, and their options are very limited. This trial exists to see whether this specialized transplant approach can offer a real cure for patients who would otherwise have no good treatment options.
You likely qualify if…
You likely don't qualify if…
If you are selected for this trial, you will undergo a two-stage surgical procedure at the hospital. In the first stage, your surgeon will perform an operation to tie off blood flow to the right side of your liver and remove cancer from the left side, causing the remaining liver to grow. In the second stage, typically several weeks later, you will receive a partial liver transplant from your living donor. After transplant, you will have regular follow-up visits with the transplant team to monitor your health, check for cancer recurrence, and manage any complications for at least three years.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Germany