Plain-English translation of NCT03494946 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a research study testing whether liver transplantation might help patients with colorectal cancer whose cancer has spread to the liver in ways that cannot be surgically removed. Right now, these patients are usually treated with alone. This trial will randomly assign half the patients to receive a liver transplant (if a donor liver becomes available) and half to continue with or other standard treatments, to see which approach helps people live longer.
When colorectal cancer spreads to the liver and cannot be removed by surgery, the outlook is poor with alone. Doctors want to know whether replacing the diseased liver with a healthy donor liver might give these patients a better chance of surviving longer.
You likely qualify if…
You likely don't qualify if…
If you are chosen for this trial, you will be randomly assigned to one of two groups. One group will be placed on a waiting list for a liver transplant and will start additional or other treatments while waiting; if a liver becomes available within 3 months, you will receive the transplant. The other group will continue with , targeted therapy, or other available treatments without transplant. Either way, you will have regular visits with the study team to check your health, have blood tests, and have imaging scans to see how you are responding to treatment.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
Norway
Sponsor
Oslo University Hospital
Enrollment target
~30 participants
Started
December 2016
Primary completion
January 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Magnus Smedman, MD
Oslo University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.