Plain-English translation of NCT03525054 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand whether analyzing the way a person speaks—specifically their word choice and grammar—can help predict who will develop psychosis or schizophrenia. This study will record an interview with participants at risk for psychosis, then use computer software to look for subtle patterns in speech that might signal a higher chance of developing the condition.
Right now, doctors can identify people at high risk for psychosis, but they don't have a reliable way to predict who will actually develop schizophrenia. This study explores whether speech patterns—which reflect how the brain is working—might be an early warning sign that researchers could use to help identify and support at-risk patients sooner.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will have a medical interview that will be audio-recorded. The researchers will transcribe and analyze your speech using computer software to look for patterns in your word choice and grammar. You may be asked to stop taking certain psychiatric medications for one week before your visit (with medical supervision). The study will follow you over time to see whether the speech patterns identified at the start predict any changes in your mental health.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
France
Sponsor
University Hospital, Brest
Enrollment target
~215 participants
Started
May 2018
Primary completion
May 2030
Age range
15 Years – 30 Years
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Christophe LEMEY, Doctor
University Hospital, Brest
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.