Plain-English translation of NCT03546829 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is testing whether — an antibiotic — combined with precision radiation therapy can safely help patients whose lung cancer has started growing again in a limited number of spots after their first round of cancer treatment. Researchers believe that might work alongside radiation to improve outcomes. Participants will receive the medication for a week before radiation starts and for a month after, while providing blood and stool samples so doctors can monitor safety.
When lung cancer comes back in just a few spots after initial immunotherapy or targeted drug treatment, doctors want to know if they can control it better by combining radiation with this medication. This trial is exploring a new approach to see if the medication makes the radiation therapy more effective and safe.
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You will start taking one week before your radiation therapy begins, and continue it for one month after radiation starts. Throughout the study, you will have blood and stool samples collected at specific timepoints so researchers can monitor how the medication and radiation affect your body. Your participation involves receiving your radiation treatment as planned while taking the medication and providing these samples — typically a commitment of several weeks to a couple of months.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
United States