Plain-English translation of NCT03573089 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether keeping phosphate levels very low (using phosphate binders) is better than keeping them at a moderate level in people whose kidneys no longer work and need dialysis. Right now, doctors recommend trying to lower phosphate levels, but we don't have strong evidence that this actually helps patients feel better or live longer. This study will follow 3,600 dialysis patients randomly assigned to one of two phosphate targets to find out.
People on dialysis often have too much phosphate in their blood, which is linked to heart problems and death. However, nobody has proven that aggressively lowering phosphate actually improves what matters most to patients—like how long they live, how they feel, or their quality of life. This trial exists to answer that question.
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You will be randomly assigned to either a 'low phosphate' group or a 'moderate phosphate' group. Your doctor will adjust your phosphate-lowering medication to help you stay within your assigned target range. You'll continue your regular dialysis appointments and clinic visits, where your phosphate levels will be monitored. The study will track whether you have any heart problems, how you feel, and your quality of life over time.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Australia