Plain-English translation of NCT03586518 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying a new heart imaging technique called native T1 mapping MRI to see if it can reliably detect scarring in the hearts of people with end-stage kidney disease who are on dialysis. This non-invasive scan uses magnetic resonance imaging (no contrast dye needed) to measure changes in heart tissue. The study aims to validate this imaging method by comparing scan results with heart tissue samples examined after death in patients who consent to heart donation for research.
People with advanced kidney disease often develop heart scarring, which can lead to serious heart problems. Current methods to detect this scarring are limited. Researchers believe this new imaging technique could become a valuable, non-invasive tool to identify and monitor heart damage in dialysis patients — but it needs to be tested and validated first before it can be used in routine care.
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If you qualify, you would have one cardiac MRI scan, which involves lying still inside an imaging machine for about 45 minutes while it takes detailed pictures of your heart. The scan is painless and does not use radiation or contrast dye. You would be asked to complete the scan as part of your care, and you would need to formally consent to donating your heart for research after your death so researchers can compare your scan results with actual heart tissue.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
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