Plain-English translation of NCT03587831 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a weight loss surgery called vertical sleeve gastrectomy, combined with intensive lifestyle counseling, can help heal a fatty liver condition called non-alcoholic steatohepatitis (NASH). Some participants will receive the surgery plus lifestyle support, while others will receive lifestyle counseling alone. Both approaches aim to help your liver by reducing excess weight.
Fatty liver disease is a serious condition that develops when too much fat builds up in the liver, often related to obesity and diabetes. Doctors want to know if weight loss surgery might be an effective new treatment to reverse liver damage, since traditional approaches to treating this condition are limited.
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You will start with screening visits that include blood tests, a food and exercise log, and a liver biopsy to confirm your diagnosis. Then you will be randomly assigned to one of two groups: either receive weight loss surgery plus lifestyle counseling, or receive intensive lifestyle counseling alone. Both groups will participate in counseling focused on nutrition and exercise for one year, with follow-up visits to monitor your progress. At the end of 12 months, you will have a second liver biopsy to see if your liver has improved.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States