Plain-English translation of NCT03600662 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether repairing the aortic valve using a technique called trileaflet reconstruction works as well as replacing it with a biological prosthesis (St. Jude Medical Trifecta GT). Both are surgical options for people with moderate to severe aortic valve disease. The study will compare how well each approach helps patients breathe better and live fuller lives.
Current treatment for severe aortic valve disease usually involves replacing the valve with a biological prosthesis, but repairing your own valve tissue may be another good option. This trial exists to see if valve repair is just as effective as valve replacement, which could give patients more choices for their care.
You likely qualify if…
You likely don't qualify if…
If you qualify and enroll, you will receive one of two treatments: aortic valve repair using your own tissue, or aortic valve replacement with a biological prosthesis. Your surgeon will determine which approach is best for your specific situation. After surgery, you will have follow-up visits to monitor how well the treatment is working and how you are feeling.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
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