Plain-English translation of NCT03644732 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is collecting brain activity recordings from people with drug-resistant epilepsy who are undergoing surgery planning. Researchers use special electrodes placed inside the brain to measure how different brain regions handle complex cognitive tasks like face recognition and attention — activities that standard testing methods cannot fully evaluate. The goal is to create a detailed map of human brain function to help doctors plan safer, more effective epilepsy surgery.
For many people with drug-resistant epilepsy, standard non-invasive tests don't provide enough information to plan surgery safely. This study fills that gap by recording brain activity during complex thinking tasks, allowing doctors to better understand which brain regions are essential for daily cognitive function and should be protected during surgery.
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As a participant, you would undergo the standard electrode implantation procedure for your epilepsy surgery evaluation. While the electrodes are in place, you will be asked to complete several cognitive tasks — such as recognizing faces, paying attention to visual or auditory cues, and other thinking exercises. Researchers will record your brain activity during these tasks using advanced imaging technology. Your brain recordings will then be added to a growing atlas to help future patients and doctors understand how the brain works during complex thinking.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
France
Sponsor
University Hospital, Grenoble
Enrollment target
~200 participants
Started
April 2018
Primary completion
March 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in March 2024.
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Central contact
Philippe Kahane, MD/PhD
University Hospital, Grenoble
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.