Plain-English translation of NCT03659448 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Neoplasms research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing , a special dye that glows under infrared light and helps surgeons see cancer cells more clearly during surgery for colorectal cancer. Some patients will receive this medication before surgery so surgeons can use special cameras to spot tumors that might be hidden from regular light. The researchers want to know if this glowing dye helps surgeons find and remove more cancer than they would with standard surgical lighting alone.
During colorectal cancer surgery, surgeons can sometimes miss small tumors or areas of cancer that spread because they're hard to see with the naked eye. This medication aims to make those hidden cancers glow so surgeons can be more thorough and complete in removing all the disease.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will either receive an injection of the study medication before your scheduled colorectal cancer surgery, or you will have standard surgery without it. If you receive the medication, your surgical team will use both regular surgical lighting and special infrared cameras during your operation to look for cancer. The surgery itself proceeds as normal — the medication simply helps your surgeon see better. Your participation ends after the surgery is complete.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
United States