Plain-English translation of NCT03675893 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , a medication that stops cancer cell growth, works better when combined with (a hormone therapy) and possibly with other drugs like or in treating endometrial cancer. The researchers want to learn which combinations work best at slowing or stopping cancer cell growth in people whose cancer has returned, spread to other parts of the body, or hasn't responded to standard treatments.
While these medications have been approved for other types of cancer or diseases, they have not yet been proven effective together for endometrial cancer. This trial exists to see if combining these treatments in new ways can help patients whose cancer is no longer controlled by standard options.
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You will take one or more study medications by mouth, either once or twice daily, depending on which treatment group you are assigned to. Some participants may also receive a medication as an intravenous infusion on certain days of a 28-day cycle. You will have regular visits with your doctor for blood tests, scans, and physical exams to monitor how well the treatment is working and watch for side effects. The exact duration depends on how your cancer responds and how well you tolerate the medication.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States