Long-term safety study of an implant delivering eye medication for vision loss

This is a long-term safety study of an implanted device called the Port Delivery System that releases ranibizumab, a medication that helps slow vision loss from age-related macular degeneration. The study follows people who received this implant in earlier trials to see how safe and well it works over time. Researchers are also testing whether a laser treatment can help prevent a side effect called bleeding inside the eye.

Currently, people with this eye condition need frequent injections into the eye—sometimes every month—to receive their medication. This implant was designed to reduce the number of injections needed by delivering the treatment automatically over several months, making treatment easier and less burdensome for patients.