Plain-English translation of NCT03694626 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Light sensitivity — difficulty tolerating bright light — is a common problem for people with traumatic brain injury, migraines, and other conditions, but doctors currently have limited tools to measure it objectively. This study is testing a new framework using specialized equipment like cameras, electrical sensors, and wearable devices to objectively measure how your eyes and nervous system respond to light. If successful, this approach could help doctors better understand what causes light sensitivity and more effectively treat it.
Right now, doctors rely mainly on patients' reports to diagnose and monitor light sensitivity, which can be subjective and difficult to measure over time. This research aims to create objective, measurable ways to assess light sensitivity so that treatment can be more precise and effective.
You likely qualify if…
You likely don't qualify if…
You would come to a study visit where researchers will use cameras to record how your face responds to light, place small electrical sensors on your skin to measure muscle and eye responses, and have you wear a special wristwatch device that monitors your heart rate and skin conductance while they expose your eyes to light. The testing is non-invasive and painless — no injections, medications, or procedures are involved. The exact duration of your visit will depend on the study, but you can expect measurements and observations of how your eyes and body naturally respond to light under controlled conditions.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Sponsor
Randy Kardon
Enrollment target
~120 participants
Started
July 2019
Primary completion
January 2028
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Julie Nellis, BSN
Randy Kardon
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.