Plain-English translation of NCT03718936 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at Mount Sinai are working to better understand ADNP syndrome and how ADNP gene variations affect development, behavior, and brain function. This study asks people with ADNP gene changes—and their biological siblings—to complete a thorough series of medical, behavioral, and sensory tests over three days. The goal is to create a clear picture of how this genetic difference affects each person, so doctors can eventually offer better support and treatment.
Very little is known about how ADNP gene variations affect the brain and behavior across different ages. This research will help doctors recognize patterns, understand why symptoms vary from person to person, and eventually develop better ways to help people with this condition.
You likely qualify if…
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You (or your child) would visit the research center for three days to complete a battery of assessments. These include behavioral observations, interviews about developmental history, physical exams, a hearing and vision evaluation, brain wave monitoring (EEG), and eye-tracking tests. You'll also be asked to provide a blood or saliva sample for genetic research. If you have biological siblings, they're invited to participate in some of the sensory tests as well.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
United States
The Seaver Foundation, Autism Science Foundation
Enrollment target
~30 participants
Started
November 2017
Primary completion
March 2027
Age range
2 Years and older
Last updated on clinicaltrials.gov in May 2025.
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Central contact
Tess Levy
Icahn School of Medicine at Mount Sinai
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.