Plain-English translation of NCT03737786 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
SEACOAST 1 is testing two different anesthesia strategies during an emergency procedure to remove blood clots from the brain in stroke patients. One approach uses mild elevation of carbon dioxide levels during anesthesia, while the other maintains normal carbon dioxide levels. Researchers want to see if the slightly elevated carbon dioxide approach helps preserve blood flow to the brain and improves patient outcomes.
Stroke caused by blood clots is a medical emergency, and doctors often use anesthesia during the clot removal procedure. Scientists believe that mild elevation of carbon dioxide during anesthesia might help maintain better blood flow around the blocked vessel, potentially leading to better recovery.
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If you qualify and enroll, you will receive the emergency clot removal procedure with anesthesia as planned—the main difference is which type of anesthesia approach your anesthesia team uses. Your vital signs, blood pressure, oxygen levels, and brain activity will be carefully monitored throughout the procedure. After the procedure, you will have follow-up visits to assess your recovery and neurological function at set timepoints.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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