Plain-English translation of NCT03740503 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study looks at tumor samples from cancer patients who had exceptional responses — either much better or much worse than expected — to their cancer treatment. By studying the genetics of these tumors, researchers hope to understand why some people respond dramatically differently to the same therapy. This knowledge could eventually help doctors predict who will benefit most from specific treatments.
Doctors have noticed that patients with very similar cancers often respond very differently to the same treatment — some improve dramatically while others don't improve at all. This trial exists to uncover the genetic reasons behind these differences, which could one day help predict which patients will respond best to particular therapies.
You likely qualify if…
You likely don't qualify if…
Your participation is straightforward — researchers will access tumor tissue that was already removed and stored during your cancer treatment. They will perform genetic testing on this existing tissue sample to identify features that may explain your treatment response. There are no new procedures, visits, or medications involved; this is purely a study of samples already in storage.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Canada
Enrollment target
~100 participants
Started
November 2013
Primary completion
November 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Celeste Yu
Princess Margaret Cancer Centre
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.