Plain-English translation of NCT03752840 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Age-related Macular Degeneration research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a large community-based study testing whether more thorough eye screening can prevent vision loss from three common eye diseases: age-related macular degeneration, diabetic retinopathy, and glaucoma. Some participants will receive basic vision testing, while others will receive additional advanced eye imaging and pressure tests. The study will follow participants for 9 years to see whose vision stays healthier.
Many older adults have serious eye diseases but don't know it until they've already lost significant vision. This study wants to find out whether catching these diseases earlier with better screening tools can actually prevent vision loss and help people keep their sight longer.
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You'll have your vision checked at a baseline visit and again 9 years later. If you're in the more intensive screening group, you'll also receive advanced eye imaging and eye pressure testing to detect diseases early. If any problems are found, you'll be referred to an eye hospital for follow-up care and treatment. If you have vision problems at the final visit, you'll receive a comprehensive eye exam to understand why.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States
Sponsor
University of California, San Francisco
Collaborators
Seva Foundation
Enrollment target
~60,200 participants
Started
April 2019
Primary completion
August 2029
Age range
60 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Krisianne M Aromin, BS
University of California, San Francisco
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.