Plain-English translation of NCT03778944 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When you receive a kidney transplant, the surgery and anesthesia used during the operation can affect how well your new kidney functions afterward. This trial compares three different approaches — using Mannitol, using Dopamine, or ensuring adequate hydration — all given during your transplant surgery to see which one best helps protect and enhance your new kidney's function.
Kidney transplantation is the best treatment for people with end-stage kidney disease, but doctors want to find the best way to protect the transplanted kidney during surgery. This trial will help identify which approach most effectively preserves kidney function and blood flow right from the start.
You likely qualify if…
You likely don't qualify if…
You will be enrolled in the study at the time of your kidney transplant surgery. During surgery, you will randomly receive one of three approaches: a Mannitol infusion, a Dopamine infusion, or careful fluid management — whichever your group is assigned to receive. After surgery, the doctors will monitor how well your new kidney works by checking blood tests and other kidney function measures as part of your standard post-transplant care.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Egypt
Sponsor
Nazmy Edward Seif
Enrollment target
~60 participants
Started
December 2018
Primary completion
December 2026
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nazmy E Seif, MD
Kasr Al-Ainy Hospital, Cairo University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.