Plain-English translation of NCT03789253 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at National Taiwan University Hospital are studying the genetics of low-risk prostate cancer to understand why some men's cancers stay stable while others progress to more aggressive forms. By comparing tissue samples from men who had cancer progression with those who didn't, the team hopes to identify genetic markers that can predict which patients need more intensive treatment earlier. This could help doctors make better decisions about monitoring versus aggressive treatment for newly diagnosed patients.
Many men are diagnosed with slow-growing prostate cancer that may never cause serious harm, but doctors currently struggle to predict which patients' cancers will progress and which will remain stable. This research aims to find genetic 'warning signs' that can help doctors personalize treatment decisions and avoid unnecessary aggressive therapy for some patients while catching dangerous progression early in others.
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You would participate in research using tissue samples already collected from your prostate biopsies at the hospital. Researchers will analyze the genetic material in these samples to identify patterns that predict cancer progression. Your involvement is primarily observational—the hospital team will review your medical records and biopsy results over time, comparing genetic changes between patients whose cancer progressed and those whose cancer remained stable.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
Taiwan