Targeted nutrients to improve activity and quality of life in COPD

Plain-English translation of NCT03807310 on ClinicalTrials.gov ↗ · Source last updated January 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This study is testing whether a special nutrient supplement called a Long-drink can help people with COPD (chronic obstructive pulmonary disease) feel better and be more active. Many people with COPD struggle with weakness, poor nutrition, and difficulty moving around. Researchers believe this medication might help by improving how your gut, muscles, and brain work together.

People with COPD often have poor nutrition and reduced physical activity, which makes their disease worse and lowers their quality of life. This trial is trying to find out if the medication can improve these problems and help patients feel healthier overall.

Do you qualify?

You likely qualify if…

you have been diagnosed with moderate to very severe COPD
your COPD is medically stable (not in an active flare-up)
you are at least 18 years old
you are willing to stop taking vitamin D or fatty acid supplements during the trial
you can commit to taking a daily supplement and attending monthly counselling sessions

You likely don't qualify if…

you are allergic to or cannot tolerate any ingredients in the supplement
you have had a hospital admission in the past 4 weeks
you have had a COPD flare-up requiring oral steroids or antibiotics in the past 4 weeks
you have a digestive system condition that affects how your body absorbs nutrients (such as inflammatory bowel disease or short bowel syndrome)
you have had lung cancer, dementia, or a recent stroke or brain condition

What participation looks like

If you join, you will take either the nutrient supplement or a placebo drink once daily for several months and attend monthly counselling sessions focused on healthy habits and lifestyle changes. You will have test days where researchers measure your physical activity, mental health, and take blood samples using non-invasive measurements. The time commitment is mainly the daily supplement, the monthly visits, and the test-day appointments.

AI-generated summary from trial data · Jun 5, 2026 · Not medical advice

Trial locations(1 site)

Netherlands

Maastricht University Medical Centre+ (MUMC+), Maastricht, Limburg