Plain-English translation of NCT03813862 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
OPERA is a large research project that gathers information from patients' medical records across the country. Researchers will study this information to learn more about how different chronic diseases are treated and what outcomes patients have, so doctors can provide better care in the future.
Doctors need better tools to understand which treatments work best for different patients with chronic illnesses, and how to help patients stay engaged in their care. This study aims to create those tools by looking at real-world patient information.
You likely qualify if…
You likely don't qualify if…
If you join this study, your existing medical records from your doctor's office will be included in a large database with information from many other patients. You won't need to come to extra appointments or take any new medications — researchers will simply study your medical information (without your name attached) to learn how to help patients with chronic diseases. The study is ongoing, so your participation can continue as long as you receive care at a participating practice.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Enrollment target
~2,000,000 participants
Started
December 2013
Primary completion
November 2035
Age range
0 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Gregory Fusco, MD
Epividian
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.