Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

Active, not recruiting

Plain-English translation of NCT03814746 on ClinicalTrials.gov ↗ · Source last updated June 2026 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

Trial locations(59 sites)

United States

Childrens Healthcare of Atlanta, Atlanta, Georgia

Boston Medical Center, Boston, Massachusetts

Levine Cancer Insitute Carolinas Healthcare System, Charlotte, North Carolina

Univ of Tenn Health Sciences Ctr, Memphis, Tennessee

U of TX Health Science Ct, Houston, Texas