Plain-English translation of NCT03822741 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking for the genetic reasons why some newborns and infants develop seizures. Researchers will perform genetic testing on babies with seizures that started before one year of age to identify specific genetic changes that may be causing the seizures. By understanding the genetic basis of these seizures, doctors hope to develop more targeted, personalized treatment strategies that address the root cause rather than just treating the symptoms.
Currently, doctors treat seizures based on how they look and behave, rather than what is actually causing them. This treatment often just prevents seizures from happening rather than fixing the underlying problem. This study exists to identify the genetic causes of seizures in newborns so that, in the future, doctors can develop treatments tailored to each child's specific genetic condition.
You likely qualify if…
You likely don't qualify if…
If your child qualifies for this study, you would provide a genetic sample (usually blood or saliva) so researchers can perform advanced genetic testing to look for the causes of the seizures. The study involves genetic analysis of your child's sample and a review of medical history and seizure records. Researchers will then share findings about what genetic changes may be responsible for your child's seizures, which could help guide future treatment decisions.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
China
Sponsor
Children's Hospital of Fudan University
Enrollment target
~2,000 participants
Started
August 2016
Primary completion
December 2026
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Wenhao Zhou, Doctor
Children's Hospital of Fudan University
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