Plain-English translation of NCT03826264 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a long-term registry study that tracks patients undergoing TAVR (transcatheter aortic valve replacement), a minimally invasive procedure to repair or replace a damaged aortic valve without open-heart surgery. Researchers at hospitals in Korea, Taiwan, and the United States are collecting information from thousands of patients to understand how well this treatment works over 10 years and what outcomes patients experience.
Many patients with aortic valve disease need treatment, but doctors want to understand the long-term safety and effectiveness of this newer, less invasive valve replacement approach compared to traditional surgery. This registry helps answer important questions about whether the treatment benefits last over time.
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If you join, you'll receive the heart valve replacement procedure as part of your regular medical care at one of the participating hospitals in Seoul, Stanford, Northwestern, or Taipei. After the procedure, you'll have periodic follow-up visits and check-ins where doctors will monitor how you're doing and collect information about your heart health. Some participants from an earlier Asian registry may continue their participation for up to 10 years of follow-up.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
China
South Korea
Sponsor
Duk-Woo Park, MD
Collaborators
CardioVascular Research Foundation, Korea
Enrollment target
~10,000 participants
Started
June 2019
Primary completion
December 2035
Age range
19 Years and older
Last updated on clinicaltrials.gov in January 2026.
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Central contact
Duk-woo Park, MD
Stanford University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.