Plain-English translation of NCT03826693 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether —a gas sometimes used in medical settings—might help people with obsessive-compulsive disorder (OCD) feel better quickly. OCD causes unwanted thoughts and repetitive behaviors that can severely impact daily life. Researchers want to see if breathing in for one hour could bring rapid relief from OCD symptoms.
Most current OCD treatments take weeks or months to work. This trial exists because there is a real need for treatments that can help people feel better much faster, especially during severe episodes when symptoms are causing significant distress.
You likely qualify if…
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If you join this study, you will come in for a session where you'll breathe a mixture of oxygen and either or a placebo gas for 60 minutes. You won't know which mixture you're receiving. The researchers will monitor you during and after the session to see how you feel and whether your OCD symptoms improve. You'll need to be able to be treatment-free for a certain period as part of the study design.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States
Testing effectiveness
Sponsor
Stanford University
Collaborators
Brain & Behavior Research Foundation
Enrollment target
~45 participants
Started
April 2021
Primary completion
September 2026
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Pavithra Mukunda, MS
Stanford Univeristy
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.