Plain-English translation of NCT03833921 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing (a medication that blocks male hormones) combined with low-dose in men with newly diagnosed advanced prostate cancer. Researchers want to understand how well this medication works and whether its effectiveness differs based on a patient's race or ethnicity, how quickly PSA levels drop, and certain genetic differences in how the body processes hormones.
Advanced prostate cancer that hasn't been treated with hormone therapy has limited treatment options. Doctors want to understand whether this medication works equally well for all patients, or whether some groups may benefit more or less than others, so they can personalize treatment recommendations.
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You would take the medication by mouth daily (one 1000 mg tablet of and two 5 mg tablets of per day) alongside your regular hormone-blocking injections or therapy. You would continue this treatment until your cancer progresses or your doctor decides to stop. Throughout the study, you'll have regular check-ups, blood tests to measure PSA levels, and imaging scans to monitor how well the medication is working.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
United States