Plain-English translation of NCT03839992 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is testing whether a special type of breathing test can detect early airway damage in children with cystic fibrosis. Many children have normal results on standard lung tests, but researchers believe they may have hidden damage to their smallest airways that current tests miss. This research uses detailed measurements of how air flows out of the lungs to catch this early damage before it becomes a bigger problem.
Children with cystic fibrosis often seem healthy based on standard breathing tests, but small airways deep in the lungs may already be damaged. Catching this damage earlier could help doctors treat and slow the disease progression before symptoms become severe.
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If you join this study, you will complete specialized breathing tests that measure how air flows out of your lungs at different levels. The tests are non-invasive and painless—you simply breathe into a machine that records detailed measurements. Researchers will compare your results to see if they can detect early airway damage that standard tests might miss.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Collaborators
Miller Children's & Women's Hospital Long Beach, Stony Brook University
Enrollment target
~100 participants
Started
April 2018
Primary completion
April 2027
Age range
5 Years – 40 Years
Last updated on clinicaltrials.gov in October 2023.
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Central contact
Arthur F Gelb, MD
University of California, Los Angeles
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