Plain-English translation of NCT03840083 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how sleep helps our brains store and remember information — and whether this process changes as we get older. This study will have you complete memory tasks (like learning word pairs or patterns) and sometimes get brain imaging, then measure how well you remember after sleeping or staying awake for the same amount of time. The goal is to learn whether sleep's role in memory consolidation differs for younger versus older adults.
Scientists know that sleep is important for memory, but they don't fully understand how this process changes with age. Understanding these differences could eventually help us prevent memory problems associated with aging and neurodegenerative diseases like Alzheimer's.
You likely qualify if…
You likely don't qualify if…
You will complete several experiments involving memory tasks — such as learning word pairs or motor sequences — combined with either a nap or overnight sleep, or a period of staying awake. Some experiments will include brain imaging (MRI scans) to see which parts of your brain are active during learning and remembering. Testing may occur over multiple visits, and you'll need to maintain a regular sleep schedule during the week before each session.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States
Sponsor
University of Massachusetts, Amherst
Enrollment target
~584 participants
Started
July 2018
Primary completion
July 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in April 2025.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.