Plain-English translation of NCT03841799 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Researchers are studying how bacteria in your gut and immune cells in your colon may play a role in colorectal cancer development. This study will collect tissue samples during your planned surgery and analyze them to understand the relationship between your gut microbiota, your immune system, and cancer growth. The goal is to find new ways to predict and treat colorectal cancer more effectively.
Doctors have noticed that people with colorectal cancer have different gut bacteria than healthy people, and that certain bacteria may help or harm the immune system's ability to fight cancer. Better understanding this connection could lead to new treatments, especially immunotherapy options that work better for some patients than others.
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If you qualify, you will undergo your planned colorectal surgery as scheduled. During or after surgery, researchers will collect small tissue samples from your colon for analysis. You will also share relevant medical information and records. The study does not require extra visits beyond your normal cancer care appointments—the tissue collection happens as part of your existing surgical procedure.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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