Frozen capsules of donor stool material for ulcerative colitis

This trial is testing whether a treatment called faecal microbiota filtrate (processed material from healthy donor stool) or faecal microbiota (whole donor stool material), delivered as frozen capsules you swallow, can help people with moderate ulcerative colitis feel better and heal their colon. The idea is based on research showing that people with ulcerative colitis have imbalances in their gut bacteria, and adding healthy bacteria from donors might restore balance and reduce inflammation.

Current treatments for ulcerative colitis don't work well enough for everyone, and some people's disease keeps coming back. This medication aims to address the root problem—an imbalance in gut bacteria—rather than just treating symptoms, offering hope for people whose disease hasn't responded to standard therapies.