Plain-English translation of NCT03845205 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After a liver transplant for severe alcoholic hepatitis, returning to alcohol use is a serious risk. This trial compares two approaches: standard care (where doctors tell you to stop drinking) versus an integrated alcohol treatment program that includes computer-based counseling in the hospital, nurse support at your regular transplant visits, and at-home online therapy with text message reminders.
Many liver transplant patients struggle with alcohol use after surgery—some return to drinking within a few years. While doctors have focused on preparing patients before transplant, far less attention has been paid to supporting them afterward, even though that's when relapse is most dangerous.
You likely qualify if…
You likely don't qualify if…
If you join, you'll receive standard transplant care plus additional alcohol support. This includes a computer-based counseling session before you leave the hospital, brief counseling from a nurse at each of your regular transplant follow-up visits, and seven online therapy sessions you can do at home, supported by text messages tailored to your needs. The whole program runs alongside your regular transplant care and blood work monitoring.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
United States
Johns Hopkins University
Collaborators
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Enrollment target
~200 participants
Started
November 2020
Primary completion
June 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
MARY E MCCAUL, PhD
Johns Hopkins University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.