Plain-English translation of NCT03860857 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
The BEACoN Study is investigating how the brain changes as we age and what factors lead to memory and thinking problems later in life. Researchers will use specialized brain scans (PET and MRI) and cognitive tests to look for early signs of brain changes related to Alzheimer's disease in healthy older adults who currently have normal thinking and memory. The goal is to find the best combination of tests that can predict who might develop cognitive decline in the future.
Currently, doctors don't have good ways to predict who will develop memory and thinking problems as they age. By studying healthy older adults now and following them over time, researchers hope to identify early warning signs that could help doctors intervene sooner and develop better treatments for cognitive decline.
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If you join this study, you would come in for visits where you'll undergo brain imaging scans (including a PET scan to look for amyloid and tau proteins, and an MRI to look at brain structure) and complete memory and thinking tests. Your first visit includes all the scans and cognitive testing, and you'll return at one year for repeat MRI and tau scans plus additional testing. The study aims to track how your cognition changes over time to identify the best tests for predicting cognitive decline.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
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