Plain-English translation of NCT03867539 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether Exparel, a long-acting numbing medication, can control pain effectively after carpal tunnel surgery without needing opioid painkillers. You would receive either standard care (a regular numbing shot plus opioid pills) or the new treatment (Exparel injection with no opioid prescription). Both groups also receive education about pain expectations after surgery.
The nation is facing an opioid crisis, and doctors are looking for safer ways to manage pain after surgery. Since carpal tunnel surgery is very common, proving that this medication works without opioids could help hundreds of thousands of patients avoid unnecessary opioid exposure each year.
You likely qualify if…
You likely don't qualify if…
You would have carpal tunnel surgery and receive either standard numbing plus opioid pain pills, or the new long-acting numbing injection without opioids. Before surgery, you'll receive education about realistic pain expectations. After surgery, you'll track your pain levels and any pain medication you use for three days, helping the researchers understand how well each approach works.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
United States