Plain-English translation of NCT03875625 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether weight loss surgery or a guided lifestyle program (including diet and exercise coaching from a nutritionist) can improve fatty liver disease in people with obesity. The study will track changes in fat deposits throughout the body and in the liver, as well as cholesterol and blood sugar levels over one year.
Many people with obesity develop fatty liver disease, which can lead to serious liver damage. The researchers want to understand why some obese patients develop this condition and others don't, and whether the amount of brown fat in your body might protect you — knowledge that could lead to better treatments.
You likely qualify if…
You likely don't qualify if…
You will join one of four groups: bariatric surgery, nutritionist-led lifestyle coaching for severe obesity, nutritionist-led lifestyle coaching for mild obesity, or standard care. Before starting treatment, you'll have an MRI scan and blood tests. You'll then receive your assigned treatment for one year, with follow-up MRI scans and blood tests at 6 and 12 months to measure changes in body fat, liver fat, and cholesterol.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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