Plain-English translation of NCT03919552 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether carboplatin, a chemotherapy drug, can be used as an alternative to cisplatin when treating advanced nasopharyngeal cancer (a type of throat cancer). Both drugs will be given along with radiation therapy and another chemotherapy drug called docetaxel. The trial will compare how well each medication works and how safe each one is for patients.
Cisplatin has been the standard chemotherapy drug used for this type of cancer, but it can cause serious side effects, especially in the kidneys and hearing. This trial is exploring whether carboplatin, which may have a safer side effect profile, can work just as well.
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You will be randomly assigned to receive either carboplatin or cisplatin as your chemotherapy drug. Before radiation therapy begins, you will receive two cycles of chemotherapy (the assigned drug plus docetaxel) given intravenously every three weeks. Then you will undergo radiation therapy combined with three more cycles of the same chemotherapy, given every three weeks during your radiation treatment. Throughout the trial, you will have regular clinic visits and blood tests to monitor your health and side effects.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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