Plain-English translation of NCT03935646 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing how Adderall IR (a prescription stimulant commonly used for ADHD) affects your ability to focus, remember things, and your overall mood. The study compares the effects of the actual medication against a placebo (a pill with no active ingredient) in college students — some with ADHD and some without. Researchers want to understand exactly how this medication works in the brain and body over a short period of time.
While stimulant medications like this one are prescribed to many college students, doctors still need to better understand how these drugs affect thinking, attention, and emotional well-being in young adults. This trial will help fill that knowledge gap so that prescribing decisions can be more informed.
You'll come to the university for three appointments. At the first visit, researchers will confirm you're eligible and collect some baseline information. Then you'll have two separate experimental visits scheduled at the same time of day — one where you'll take the actual medication and one where you'll take a placebo. After taking the pill, you'll wait 90 minutes, then complete computer-based tests of your attention and memory while researchers monitor your heart rate and blood pressure. You'll be asked to avoid caffeine, alcohol, and other substances for 12 hours before each visit.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
United States