Plain-English translation of NCT03937817 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study where scientists collect small samples of blood, saliva, urine, and sometimes fatty tissue from volunteers to better understand how genetic changes in blood proteins affect diseases like sickle cell disease and malaria. The researchers want to study these samples in the lab to learn how certain genetic variants protect against or contribute to these diseases.
Scientists need access to real biological samples from people with and without these conditions to develop better tests and understand exactly how genetic variants change the way blood works. This knowledge could lead to better treatments and preventive strategies in the future.
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Depending on which samples you agree to provide, you may visit the NIH Clinical Center to give blood, saliva, or urine samples through simple collection procedures. If you volunteer for additional samples like fatty tissue or lung samples, those involve minor procedures done by trained medical staff, similar to what you'd experience at a routine doctor's visit. All of your samples will be stored and used for laboratory research to help scientists understand these blood disorders better.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States