Plain-English translation of NCT03937817 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at the National Institute of Allergy and Infectious Diseases are collecting biological samples—like blood, saliva, urine, and tissue—from healthy volunteers and people with conditions like sickle cell disease or malaria. They want to understand how variations in genes that control blood cell production affect these diseases and how the body responds to inflammation.
Scientists need to study how genetic differences in blood cells influence sickle cell disease, malaria, and other conditions involving inflammation. By analyzing samples from both healthy people and patients, researchers can better understand the mechanisms of these diseases and potentially develop better treatments.
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Depending on which samples you agree to provide, you may visit the NIH Clinical Center to donate blood, saliva, or urine, or to have a small tissue sample collected. Some participants may undergo a bronchoscopy—a procedure where doctors look inside your airways using a thin camera—to collect samples from your lungs. The study does not involve taking any medications; it is purely about collecting and storing your biological samples for research.
AI-generated summary from trial data · Oct 6, 2026 · Not medical advice
United States