Plain-English translation of NCT03952624 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study designed to help scientists better understand fatigue — not just tiredness, but the kind that significantly impacts daily life. Researchers want to learn why different people experience fatigue differently, even when they have the same disease. By studying up to 692 people with and without fatigue-causing conditions, they hope to identify the different types of fatigue and what causes them in the body.
Right now, doctors don't have a clear way to understand why some patients with the same disease experience severe fatigue while others don't. This research is trying to fill that gap by creating detailed descriptions of fatigue and finding biological clues about what drives it.
You likely qualify if…
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You'll start with a phone screening to see if you're eligible, then come to the NIH for an in-person visit. Depending on which part of the study you join, you may complete physical tests (like exercise testing or brain imaging), answer detailed questions about your fatigue and health, and provide blood samples. Some visits may require specialized tests like MRI scans or walking on a treadmill — the exact activities depend on your health status and the study group you're in.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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