Plain-English translation of NCT03959800 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is collecting biological samples — such as tumor tissue, blood, and saliva — from children who have been treated for liver cancer, along with samples from their parents and siblings. Researchers will study the genes in these samples to understand why liver cancers behave differently and to develop better ways to classify and treat them.
Childhood liver cancers are very rare, and doctors don't fully understand the genetic reasons why some tumors respond well to treatment while others don't. By collecting samples from many patients across different hospitals and countries, researchers hope to discover genetic patterns that will lead to better diagnoses and more effective treatments.
You likely qualify if…
You likely don't qualify if…
If you qualify, you or your child would donate biological samples such as a small amount of tumor tissue (if available), a blood sample, or a saliva sample. Your family members would likely do the same. You would also share medical information about the cancer diagnosis and treatment. The samples are collected once, though researchers will study them over time to look for genetic patterns.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
University of Pittsburgh
Enrollment target
~1,600 participants
Started
June 2015
Primary completion
June 2028
Age range
0 Years – 99 Years
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Morgan Paul, BSN
University of Pittsburgh
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.