Plain-English translation of NCT04002882 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Cystic Fibrosis research guide →Researchers want to understand why people with cystic fibrosis often have unusual patterns of fat and muscle in their bodies, and whether these patterns make their lungs weaker and their blood sugar control worse over time. This study will use MRI scans and other detailed body measurements to look at fat distribution and muscle mass in people with CF, comparing them to healthy volunteers who are similar in age and size. The goal is to identify whether changes in body composition are connected to lung decline and metabolic problems.
People with cystic fibrosis often struggle with maintaining healthy weight and muscle, and they're at higher risk for diabetes and lung problems. By understanding the relationship between how their bodies store fat and muscle and their overall health, researchers hope to find better ways to prevent or slow down these complications.
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If you join, you'll come in for study visits where you'll have body composition scans (using MRI and a DEXA scan), a glucose tolerance test (drinking a sugary drink and having blood drawn), and measurements of your nutrition and lung health. Some participants (about 40 out of 60 with CF) will be followed for two years with repeat visits. The study compares people with CF to 30 healthy volunteers who are matched for age, sex, and body size to help researchers understand what's different.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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