Plain-English translation of NCT04008407 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing which removal technique works best for large, flat polyps found in the colon. Doctors will use either endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) depending on how risky the polyp appears to be. The goal is to remove these polyps completely and safely while reducing the chance they come back or contain hidden cancer.
Large, flat polyps have a higher risk of containing cancer or coming back after removal compared to small polyps. While both removal techniques work well, researchers want to determine which approach is best for different types of polyps to improve cancer prevention and reduce complications.
You likely qualify if…
You likely don't qualify if…
You will have a colonoscopy where your doctor will examine your polyp carefully to assess the risk of hidden cancer. Based on this assessment, you will receive one of two removal techniques—either the standard removal method or a more advanced technique that removes the polyp in one piece. After the procedure, your polyp will be examined under a microscope, and your doctor will follow up to ensure complete removal and healing.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Australia
Sponsor
Western Sydney Local Health District
Enrollment target
~391 participants
Started
August 2017
Primary completion
August 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Michael J Bourke, MBBS
Western Sydney Local Health District
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.